Research Technician

Job Description

We are seeking a highly motivated Research technician to work on a research project funded by Alzheimer’s research UK. The successful candidate will join Dr Tatyana Shelkovnikova’s (principal investigator, PI) research team, based at the Sheffield Institute for Translational Neuroscience (SITraN). The aim of the project is to apply an optogenetic approach to develop a platform for studying frontotemporal dementia (FTD) / amyotrophic lateral sclerosis (ALS) caused by C9orf72-derived dipeptide-repeat (DPR) protein aggregation in human neurons. The ideal candidate will be a practically skilled, well-organised and committed individual with experience of mammalian cell culture, gene expression analysis and imaging-based analysis of cellular phenotypes. Previous experience in RNA biology, protein aggregation analysis, molecular cloning, human stem cell and neuronal culture would be advantageous. Team spirit and an impeccable work ethic are essential. You will conduct laboratory research under the direction of the PI and research associates. You will be expected to assist in the design, execution, and interpretation of experiments; keep excellent experimental records; prepare figures and reports regularly and present data at lab group meetings.

This post is fixed-term for 18 months and is available immediately.

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